Alice's (Yasmien Kurdi) husband, Kitkat's (Bea Binene) brother, and Brie's (Gabbi Garcia) boyfriend Lance (Derrick Monasterio) are all PDEA agents who died on a failed mission. Eventually, Alice discovers that their passing was not an accident: a powerful drug syndicate actually murdered their loved ones. Armed with special skills and help from Vin (Gil Cuerva), the three women unite to track down the syndicate and seek justice for everything they lost.