"The Seed of Love" follows the story of Bobby (Mike) who decides to have his sperm frozen due to cancer scare. He has been in a long, tedious relationship with a bratty socialite Alexa (Valerie) until Bobby finally breaks up with her. Later on, Bobby meets the optimistic and doting Eileen (Glaiza). Their love blossoms and soon, the two get married. Bobby and Eileen agree to have their child via in-vitro fertilization using his preserved sperm cell. But Alexa will do everything to destroy the couple and win her ex-boyfriend back. One day, Alexa steals the embryo of Eileen and Bobby. She does this in connivance with Peter (Boy2), her obsessed and hopeless romantic lover. Peter then implants the stolen embryo in Alexa's uterus and replaces Eileen's with a random embryo. Alexa eventually convinces Bobby that he impregnated her after a recent one-night stand. How will the truth unravel? Is it really goodbye for Eileen and Bobby's happy family? How far can Alexa and Peter go for the sake of their wrong and unfair love?